AN ER PROTEIN FUNCTIONALLY COUPLES NEUTRAL LIPID METABOLISM ON LIPID DROPLETS TO MEMBRANE LIPID SYNTHESIS IN THE ER

An ER Protein Functionally Couples Neutral Lipid Metabolism on Lipid Droplets to Membrane Lipid Synthesis in the ER

Eukaryotic cells store neutral lipids such as triacylglycerol (TAG) in lipid droplets (LDs).Here, we have addressed how LDs are functionally linked to the endoplasmic reticulum (ER).We show that, in S.cerevisiae, LD growth is sustained by LD-localized enzymes.When LDs grow in early stationary phase, the diacylglycerol acyl-transferase Dga1p moves f

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Progress in Developing Inhibitors of SARS-CoV-2 3C-Like Protease

Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).The viral outbreak started in late 2019 and rapidly became a serious health threat to the global population.COVID-19 was declared a pandemic by the World Health Organization in March 2020.Several therapeutic options have been adopted to pre

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Transcriptome-wide Identification and Expression Analysis of Brachypodium distachyon Transposons in Response to Viral Infection

Transposable elements (TEs) are the most abundant group of genomic elements in plants that can be found in genic or intergenic regions of their host genomes.Several stimuli such as biotic or abiotic stress have roles in either activating their transcription or transposition.Here the effect of the Panicum mosaic virus (PMV) and its satellite virus (

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Restrictive state laws aimed at immigrants: Effects on enrollment in the food stamp program by U.S. citizen children in immigrant families.

This paper examines whether a chilling effect of restrictive state laws aimed at immigrants creates a barrier to enrollment in the food stamp program (now called the Supplemental Nutrition Assistance Program or SNAP) for U.S.citizen children in low-income immigrant families.This analysis looks at 20 states in the continental United States from 2000

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